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Heart failure

Interatrial shunting for the treatment of heart failure

Nature Reviews Cardiology volume 13, pages 312–313 (2016)Cite this article

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Left-to-right atrial shunting is feasible, safe, and has potential beneficial effects in patients with heart failure, irrespective of their ejection fraction. These findings come from two studies published in The Lancet.

Implantation of an interatrial shunt device... could be a new strategy for the management of HFpEF

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References

  1. Del Trigo, M. et al. Unidirectional left-to-right interatrial shunting for treatment of patients with heart failure with reduced ejection fraction: a safety and proof-of-principle cohort study. Lancet 387, 1290–1297 (2016)

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  2. Hasenfuß, G. et al. A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial. Lancet 387, 1298–1304 (2016)

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Authors
  1. Irene Fernández-Ruiz
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Related links in Nature Research

Borlaug, B. A. The pathophysiology of heart failure with preserved ejection fraction. Nat. Rev. Cardiol. 11, 507–515 (2014)

Ziaeian,B.&Fonarow,G.C.Epidemiologyandaetiologyofheartfailure.Nat.Rev.Cardiol.http://dx.doi.org/10.1038/nrcardio.2016.25(2016)

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Fernández-Ruiz, I. Interatrial shunting for the treatment of heart failure. Nat Rev Cardiol 13, 312–313 (2016). https://doi.org/10.1038/nrcardio.2016.56

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