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Killing the old: cell senescence in atherosclerosis

Nature Reviews Cardiology volume 14, pages 8–9 (2017)Cite this article

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An Erratum to this article was published on 12 January 2017

This article has been updated

Atherosclerosis is a disease of ageing, and the most common cause of death in the industrialized world. Cell senescence and the therapeutic removal of senescent cells using 'senolytics' are topical areas of science and translational medicine. A new study reports surprising findings on cell senescence and atherosclerosis with important therapeutic implications.

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Figure 1: Effects of cell senescence in atherosclerosis.

Change history

  • 12 January 2017

    In the version of this article initially published online and in print, the red symbol in Figure 1 should be IL-1α, and not IL-1β. The error has been corrected for the HTML and PDF versions of the article.

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Acknowledgements

This work was funded by British Heart Foundation Grants RG/13/14/30314, FS/13/3/30038 and RG/16/8/32388, and the Cambridge NIHR Biomedical Research Centre.

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  1. Martin R. Bennett and Murray C. H. Clarke are at the Division of Cardiovascular Medicine, University of Cambridge, Box 110 ACCI, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.,

    Martin R. Bennett & Murray C. H. Clarke

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  1. Martin R. Bennett
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  2. Murray C. H. Clarke
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Correspondence to Martin R. Bennett.

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The authors declare no competing financial interests.

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Bennett, M., Clarke, M. Killing the old: cell senescence in atherosclerosis. Nat Rev Cardiol 14, 8–9 (2017). https://doi.org/10.1038/nrcardio.2016.195

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