In an analysis of electronic health records, 1.25 million patients aged ≥30 years without diagnosed cardiovascular disease experienced 83,098 cardiovascular events during follow-up (median 5.2 years). Associations between incident cardiovascular disease and blood pressure differed for systolic and diastolic blood pressures and between the 12 cardiovascular end points examined.
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References
Rapsomaniki, E. et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. Lancet 383, 1899–1911 (2014).
Kannel, W. B. et al. Systolic versus diastolic blood pressure and risk of coronary heart disease. Am. J. Cardiol. 27, 335–346 (1971).
Franklin, S. S. et al. Does the relation of blood pressure to coronary heart disease change with aging? The Framingham Heart Study. Circulation 103, 1245–1249 (2001).
Stamler, J. et al. Blood pressure (systolic and diastolic) and risk of fatal coronary heart disease. Hypertension 13 (Suppl. I), I2–I12 (1989).
Kuznetsova, T. et al. Quality control of the blood pressure phenotype in the European Project on Genes in Hypertension. Blood Press. Monit. 7, 215–224 (2002).
Li, Y. et al. Age dependency of peripheral and central systolic pressures: cross-sectional and longitudinal observations in a Chinese population. Hypertens. Res. 35, 115–122 (2012).
Li, Y. et al. Ambulatory hypertension subtypes and 24-hour systolic and diastolic blood pressure as distinct outcome predictors in 8341 untreated people recruited from 12 populations. Circulation http://dx.doi.org/10.1161/circulationaha.113.004876.
Lim, S. S. et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380, 2224–2260 (2012).
Sever, P. S. Simple blood pressure guidelines for primary care. J. Hum. Hypertens. 13, 725–727 (1999).
Gu, D. et al. Prevalence, awareness, treatment and control of hypertension in China. Hypertension 40, 920–957 (2002).
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The author acknowledges the insightful comments of his co-workers: Yanping Liu, Lutgarde Thijs, and Zhenyu Zhang (University of Leuven, Belgium).
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Staessen, J. Age-specificity of blood-pressure-associated complications. Nat Rev Cardiol 11, 499–501 (2014). https://doi.org/10.1038/nrcardio.2014.109
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DOI: https://doi.org/10.1038/nrcardio.2014.109
