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Valvular disease

Super size me? Annular size and paravalvular leak after TAVR

Paravalvular aortic regurgitation (PAR) after transcatheter aortic valve replacement is common and independently associated with increased morbidity and mortality. The determinants of PAR are uncertain, but new data extend our understanding, and a simple practice change in preprocedural imaging could help dramatically to reduce the incidence of this important complication.

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Figure 1: Simulated transcatheter aortic valve replacement with a SAPIEN® valve (Edwards Lifesciences Corporation, Irvine, CA, USA) for position optimization.


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Correspondence to Michael A. Quail.

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The authors declare no competing financial interests.

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Quail, M., Taylor, A. Super size me? Annular size and paravalvular leak after TAVR. Nat Rev Cardiol 9, 265–266 (2012).

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