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Lipids in 2012

HDL cholesterol studies—more of the same?

Studies published in 2012 in the field of HDL research have provided further evidence suggesting that a low HDL-cholesterol level, in the absence of related lipid or nonlipid risk factors, is not associated with increased risk of coronary heart disease.

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Figure 1: Mechanisms linking HDL to cardiovascular disease.

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J.-P. Després has received honoraria from Abbott, AstraZeneca, GlaxoSmithKline, Merck, and Pfizer Canada, and has acted as a consultant for Novartis, Sanofi, Theratechnologies, and Torrent Pharmaceuticals.

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Després, JP. HDL cholesterol studies—more of the same?. Nat Rev Cardiol 10, 70–72 (2013). https://doi.org/10.1038/nrcardio.2012.182

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