During 2010, several landmark studies, including the PARTNER trial, have made huge advances in the field of transcatheter aortic valve implantation. Other studies have made major contributions to the therapeutic management of young adult patients with severe aortic valve disease and of patients with asymptomatic severe mitral regurgitation.
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References
Magne, J., Lancellotti, P. & Piérard, L. A. Exercise pulmonary hypertension in asymptomatic degenerative mitral regurgitation. Circulation 122, 33–41 (2010).
Le Tourneau, T. et al. Impact of left atrial volume on clinical outcome in organic mitral regurgitation. J. Am. Coll. Cardiol. 56, 570–578 (2010).
El-Hamamsy, I. et al. Long-term outcomes after autograft versus homograft aortic root replacement in adults with aortic valve disease: a randomised controlled trial. Lancet 376, 524–531 (2010).
Webb, J. G. et al. Transcatheter valve-in-valve implantation for failed bioprosthetic heart valves. Circulation 121, 1848–1857 (2010).
Leon, M. B. et al. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N. Engl. J. Med. 363, 1597–1607 (2010).
Bonow, R. O. et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients with Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. Circulation 114, e84–e231 (2006).
Magne, J., Lancellotti, P. & Piérard, L. A. Exercise-induced changes in degenerative mitral regurgitation. J. Am. Coll. Cardiol. 56, 300–309 (2010).
El-Hamamsy, I. et al. Late outcomes following freestyle versus homograft aortic root replacement: results from a prospective randomized trial. J. Am. Coll. Cardiol. 55, 368–376 (2010).
Iung, B. et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. Eur. Heart J. 24, 1231–1243 (2003).
Rodés-Cabau, J. et al. Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience. J. Am. Coll. Cardiol. 55, 1080–1090 (2010).
Acknowledgements
P. Pibarot holds the Canada Research Chair in Valvular Heart Diseases, which is funded by the Canadian Institutes of Health Research (CIHR), Ottawa, ON, Canada, and his research projects are funded by CIHR grants MOP-57745, MOP-79342, MOP-102737, and MOP-86666.
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P. Pibarot has received grants/research support from Edwards Lifesciences, Medtronic, and Sorin Medical, and is co-investigator of the PARTNER trial.
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Pibarot, P. Evolution and revolution in risk stratification and therapy. Nat Rev Cardiol 8, 75–77 (2011). https://doi.org/10.1038/nrcardio.2010.204
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DOI: https://doi.org/10.1038/nrcardio.2010.204
