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What are the hallmarks of cancer?

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The seminal article by Douglas Hanahan and Robert Weinberg on the hallmarks of cancer is 10 years old this year and its contribution to how we see cancer has been substantial. But, in embracing this view, have we lost sight of what makes cancer cancer?

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Acknowledgements

I would like to thank D. Berman (Departments of Pathology, Oncology, and Urology at Johns Hopkins University, USA), T. Ried (Section of Cancer Genomics, National Cancer Institute, USA), D. Duelli (Department of Pathology, the Rosalind Franklin University, USA) and G. Parris (Center of Cancer Systems Biology, Tufts University, USA) for insightful comments.

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Lazebnik, Y. What are the hallmarks of cancer?. Nat Rev Cancer 10, 232–233 (2010). https://doi.org/10.1038/nrc2827

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