Abstract
Lipids can be systematically classified according to functional properties, structural features, biochemical origin or biological system. However Lipid nomenclature has yet to become a robust research tool since no rigorous definitions exist for membership of specific lipid classes. Lipids need to be defined in a manner that is systematic yet at the same time semantically explicit. We report on the reuse of existing lipid nomenclature, ontology describing chemical structure and the extension of the OWL-DL Lipid Ontology to support the classification of lipid molecules. We applied definitions, DL-axioms, to describe lipids classes and illustrate suitability of the ontology for the classification of Fatty Acyl lipids and Mycolic acids.
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Low, HS., Baker, C., Garcia, A. et al. An OWL-DL Ontology for Classification of Lipids. Nat Prec (2009). https://doi.org/10.1038/npre.2009.3590.2
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DOI: https://doi.org/10.1038/npre.2009.3590.2