Abstract
We introduce a new effective method to control hormone refractory prostate cancer cells by using an activated rubber/resin form (RB), far-infrared ray emitter, with or without sodium butyrate (SB). The growth of three human prostate cancer cell lines (Du145, PC-3 and LNCaP) was suppressed in vitro and in vivo by using RB, and the cells were eradicated with RB + 3 mM SB. G1 arrest and apoptotic pathway proteins were induced by RB with intensified expressions of apoptosis - related mRNA on cDNA microarray. RB radiates the infra-red rays of the 4 to 25 [mu]m wavelengths to an object which exert a favorable influence on a cancer control. These results may render us a new therapeutic modality in hormone refractory prostate cancer.
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Shima, H., Yamamoto, S., Qiu, J. et al. Far-infrared rays control prostate cancer cells in vitro and in vivo. Nat Prec (2008). https://doi.org/10.1038/npre.2008.1980.1
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DOI: https://doi.org/10.1038/npre.2008.1980.1