Figure 1

From: In vivo Calcium Imaging to Illuminate Neurocircuit Activity Dynamics Underlying Naturalistic Behavior

Figure 1

Optical technologies for in vivo calcium imaging in freely behaving mice. (a) Mini-epifluorescence microscope attached to a head-mounted base plate that is centered around a microendoscope implanted above a brain region of interest. (b) A fiber probe is implanted above the target brain region of interest to collect bulk changes in calcium-mediated fluorescence using fiber photometry. (c) Animals engaging in naturalistic behavior such as social interaction while fluorescent transients are measured as a read-out of neural activity with the use of microendoscopic imaging (left) or fiber photometry (right).