Figure 6

From: Cannabinoids Ameliorate Impairments Induced by Chronic Stress to Synaptic Plasticity and Short-Term Memory

Figure 6

The effects of chronic exposure to restraint stress and WIN55,212-2 on GR levels. Representative bands (taken from different gels) for the expression of GR and β-actin (upper panel) and quantitative analysis result (lower panel) of GR expression. (a) In the NAc, rats in the stress groups demonstrate significantly lower GR expression levels compared with rats in the non-stressed groups. Rats in the No Stress-Vehicle group demonstrate significantly lower GR expression levels compared with rats in the No Stress-WIN group (**p<0.01; ***p<0.001). (b) In the BLA, rats in the stress groups demonstrate significantly lower GR expression levels compared with rats in the non-stressed groups (*p<0.05; **p<0.01; ***p<0.001). (c) In the PFC, rats in the stress groups demonstrate significantly lower GR expression levels compared with rats in the non-stressed groups (***p<0.001). (d) In the CA1, rats in the Stress-Vehicle group demonstrate significantly lower GR expression levels compared with rats in non-stressed groups. Rats in the Stress-WIN group demonstrate significantly lower GR expression levels compared with rats in the No Stress-WIN group (*p<0.05; **p<0.01). (e) In the vSub, rats in the stress groups demonstrate significantly lower GR expression levels compared with rats in the non-stressed groups (**p<0.01; ***p<0.001).