Figure 4

From: Cannabinoids Ameliorate Impairments Induced by Chronic Stress to Synaptic Plasticity and Short-Term Memory

Figure 4

The effects of chronic exposure to restraint-stress and WIN55,212-2 on performance in the forced-swim test. (a) Thirty days after stress and drug injections, rats in the Stress-WIN group spend significantly less time swimming than rats in the Stress-Vehicle and No Stress-Vehicle groups (*p<0.05). (b) Twenty-four hours after stress and drug injections, rats in the Stress-Vehicle group spend significantly more time climbing than rats in the No Stress-WIN group. Rats in the No Stress-WIN group spend significantly more time immobile than rats in the Vehicle groups (**,p<0.01). (c) Ten days after stress and drug injections, there are no significant differences between the groups.