Figure 4

From: Inhibition of Hippocampal β-Adrenergic Receptors Impairs Retrieval But Not Reconsolidation of Cocaine-Associated Memory and Prevents Subsequent Reinstatement

Figure 4

The effects of β-AR blockade on retrieval are not due to non-specific effects. (a) dHipp microinfusions of nadolol (n=10) or saline (n=14) did not prevent rats from expressing a CPP during a test 24 h later. (b) Following conditioning with dHipp microinfusions of nadolol or saline (n=12), rats spent an equivalent amount of time within the nadolol-paired and saline-paired chambers. (c) Following dHipp microinfusions of a saline (n=17), a high dose of nadolol (n=16), or a low dose of nadolol (n=9), rats displayed equivalent locomotor activity during a CPP test as measured by photobeam breaks. **p<0.01.