Figure 3

From: Inhibition of Hippocampal β-Adrenergic Receptors Impairs Retrieval But Not Reconsolidation of Cocaine-Associated Memory and Prevents Subsequent Reinstatement

Figure 3

β-AR blockade in dHipp does not prevent CPP memory reconsolidation. (a) Coronal drawings (bregma, −3.24 mm) showing injector tip placements for dHipp microinfusions. (b) dHipp microinfusions (arrows) of nadolol (n=18) or saline (n=17) did not prevent rats from expressing a CPP during subsequent microinfusion-free tests. (c) Rats did not show a CPP during the final extinction test. The following day, previously saline- and nadolol-treated rats expressed cocaine-induced reinstatement of the CPP. *p<0.05 and **p<0.01.