Figure 5

From: In vivo Effects of Abused ‘Bath Salt’ Constituent 3,4-methylenedioxypyrovalerone (MDPV) in Mice: Drug Discrimination, Thermoregulation, and Locomotor Activity

Figure 5

Locomotor activity elicited by administration of 10 mg/kg MDMA at an ambient temperature of 20 °C (black circles) or 28 °C (white circles). The ‘X’ adjacent to the last data point obtained following administration of MDMA in the warm ambient environment denotes the approximate time that all mice were removed from the chambers and euthanized, in accordance with our IACUC protocol. Abscissa: points to the left of the up arrow denote baseline data before injection, presented as the mean activity observed over 1 h. Numbers refer to time, in minutes, following MDMA administration. Ordinate: mean activity counts calculated in 30 min bins.