Novel object recognition performance in wild-type mice on the 1st or 7th day of withdrawal after single or repeated (daily for 7 day) MDMA treatment (10 mg/kg, i.p.). Each graph shows the discrimination ratio in the test trial. Data represent the mean±SEM (n=5–15). *p<0.05, ***p<0.001 vs vehicle-treated mice. Vehicle includes results for mice administered saline once or repeatedly for 7 days.