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MicroRNAs in crop improvement: fine-tuners for complex traits

Abstract

One of the most common challenges for both conventional and modern crop improvement is that the appearance of one desirable trait in a new crop variety is always balanced by the impairment of one or more other beneficial characteristics. The best way to overcome this problem is the flexible utilization of regulatory genes, especially genes that provide more efficient and precise regulation in a targeted manner. MicroRNAs (miRNAs), a type of short non-coding RNA, are promising candidates in this area due to their role as master modulators of gene expression at the post-transcriptional level, targeting messenger RNAs for cleavage or directing translational inhibition in eukaryotes. We herein highlight the current understanding of the biological role of miRNAs in orchestrating distinct agriculturally important traits by summarizing recent functional analyses of 65 miRNAs in 9 major crops worldwide. The integration of current miRNA knowledge with conventional and modern crop improvement strategies is also discussed.

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Figure 1: Distribution of miRNAs and their target genes.
Figure 2: Experimentally verified miRNA:trait relationships in rice.
Figure 3: Regulatory circuits orchestrated by miRNAs in rice.

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Acknowledgements

This work was supported by the grants from the Chinese Academy of Sciences (XDA08010400), the National Key Research and Development Program of China (2016YFD0101801), and the National Natural Science Foundation of China (31571248 and 31201182). We apologize to our colleagues whose work was not included or sufficiently discussed in this article because of space restrictions.

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J.T. and C.C. wrote this article.

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Correspondence to Jiuyou Tang or Chengcai Chu.

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Tang, J., Chu, C. MicroRNAs in crop improvement: fine-tuners for complex traits. Nature Plants 3, 17077 (2017). https://doi.org/10.1038/nplants.2017.77

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