Table 1 Baseline characteristics of study subjects

From: Microvascular dysfunction in schizophrenia: a case–control study

  Schizophrenia; N (%) Control; N (%) P-value
Total sample 51 51
 Male 30 (58.8) 30 (58.8) >0.999
 Female 21 (41.2) 21 (41.2) >0.999
 Caucasian ethnicity 33 (64.7) 38 (74.5) 0.110
Cardiovascular risk factors
 Hypertension 2 (3.9) 0 (0) 0.160
 Diabetes 2 (3.9) 1 (2.0) 0.558
 Dyslipidemia 10 (19.6) 2 (3.9) 0.014
 Current smokers 23 (45.1) 22 (43.1) 0.842
 Family history of CVD 20 (39.2) 19 (37.2) 0.839
 Metabolic syndrome (ATP III definition) a 15 (29.4) 3 (5.9) 0.002
Psychotropic medications
 Antipsychotic medication use 51 (100) n/a  
 Antidepressant medication use 14 (27.4) n/a
 Mood stabilizers 7 (13.7) n/a
 Benzodiazepines 5 (9.8) n/a
 Anticholinergic medication use 6 (11.8) n/a
Other medications
 Antihypertensive medication use 6 (11.8) 0 (0) 0.012
 Lipid-lowering medication use 9 (17.7) 0 (0) 0.002
 Antidiabetic medication use 2 (3.9) 0 (0) 0.160
  1. Abbreviations: ATP III, Adult Treatment Panel III; cardiovascular disease cardiovascular disease; MET, metabolic equivalent of task.
  2. aATP III definition (three of five required): waist circumference >102 cm for males, >88 cm for females; blood pressure 130/85 mm Hg; HDL<1.04 mmol/l for males, <1.29 for females; triglycerides 1.7 mmol/l; fasting glucose 6.1 mmol/l.
  Mean s.d. Mean s.d.  
Age (years) 35.1 7.1 33.9 7.9 0.442
Disease duration (years) 13.5 6.8 n/a  
Mean body mass index (kg/m2) 30.7 7.5 24.9 4.7 <0.001
Waist circumference (cm) 101.0 15.0 80.6 12.0 <0.001
Systolic blood pressure (mm HG) 114.5 11.9 117.7 12.5 0.186
Diastolic blood pressure (mm HG) 75.2 8.6 73.9 8.1 0.443
Pack years of smoking 7.32 8.117 2.259 4.302 <0.001
  1. Abbreviations: ATP III, Adult Treatment Panel III; cardiovascular disease cardiovascular disease; MET, metabolic equivalent of task.
  2. aATP III definition (three of five required): waist circumference >102 cm for males, >88 cm for females; blood pressure 130/85 mm Hg; HDL<1.04 mmol/l for males, <1.29 for females; triglycerides 1.7 mmol/l; fasting glucose 6.1 mmol/l.
  Median 25th, 75th percentile Median 25th, 75th percentile  
Total physical activity (MET*min/week) 1,830 (1,094, 3,545) 2,680 (1,201, 7,011) 0.115
  1. Abbreviations: ATP III, Adult Treatment Panel III; cardiovascular disease cardiovascular disease; MET, metabolic equivalent of task.
  2. aATP III definition (three of five required): waist circumference >102 cm for males, >88 cm for females; blood pressure 130/85 mm Hg; HDL<1.04 mmol/l for males, <1.29 for females; triglycerides 1.7 mmol/l; fasting glucose 6.1 mmol/l.