Table 3 Asthma control and indicators of symptoms and exacerbations by treatment level

From: Asthma control and management in 8,000 European patients: the REcognise Asthma and LInk to Symptoms and Experience (REALISE) survey

  Reliever only (n=1,419) Single-drug preventer inhaler (n=1,923) Combination preventer inhaler (n=754) Combination preventer inhaler plus oral pill (n=234)
Control and indicators of symptoms
GINA-defined control level
Controlled 408 (28.8) 465 (24.2) 165 (21.9) 40 (17.1)
Partially controlled 594 (41.9) 700 (36.4) 278 (36.9) 79 (33.8)
Uncontrolled 417 (29.4) 758 (39.4) 311 (41.2) 115 (49.1)
 Normal activities affected by symptomsa
None 732 (51.6) 986 (51.3) 387 (51.3) 92 (39.3)
1 day 687 (48.4) 937 (48.7) 367 (48.7) 142 (60.7)
3 days 187 (13.2) 318 (16.5) 160 (21.2) 67 (28.6)
 Days with symptomsa
None 370 (26.1) 417 (21.7) 164 (21.8) 37 (15.8)
1 day 1,049 (73.9) 1,506 (78.3) 590 (78.2) 197 (84.2)
3 days 389 (27.4) 724 (37.6) 340 (45.1) 115 (49.1)
 Night-time awakeninga
None 801 (56.4) 1,045 (54.3) 392 (52.0) 114 (48.7)
1 day 618 (43.6) 878 (45.7) 362 (48.0) 120 (51.3)
 Reliever inhaler usea
Not used 540 (38.1) 559 (29.1) 208 (27.6) 53 (22.6)
1 times 871 (61.4) 1,297 (67.4) 501 (66.4) 172 (73.5)
3 times 430 (30.3) 786 (40.9) 326 (43.2) 112 (47.9)
10 times 38 (2.7) 139 (7.2) 64 (8.5) 23 (9.8)
Acute exacerbations
 Antibiotic use for an asthma-associated conditionb
0 698 (49.2) 860 (44.7) 334 (44.3) 69 (29.5)
1 course 721 (50.8) 1,063 (55.3) 420 (55.7) 165 (70.5)
 Oral steroid use for worsening asthmab
0 1,049 (73.9) 1,362 (70.8) 455 (60.3) 86 (36.8)
1 course 370 (26.1) 561 (29.2) 299 (39.7) 148 (63.2)
 Emergency department visit due to asthmab
0 1,243 (87.6) 1,650 (85.8) 614 (81.4) 164 (70.1)
1 visit 176 (12.4) 273 (14.2) 140 (18.6) 70 (29.9)
 Overnight hospitalisation due to asthmab
0 1,369 (96.5) 1,843 (95.8) 696 (92.3) 194 (82.9)
1 stay 50 (3.5) 80 (4.2) 58 (7.7) 40 (17.1)
  1. Data are shown as n (%) of patients. Only patients with an identifiable treatment were included.
  2. Abbreviation: GINA, Global Initiative for Asthma.
  3. aIn the previous 7 days.
  4. bIn the previous 12 months.