EXaCT-1 mutation testing statistics in IPM patient cohort. (a) Number of cases by cancer type, (b) mutation load by cancer diagnosis and (c) stage. (d) Number of gene variations by gene and by tier. (e) Commonly mutated Tier 1 and (f) Tier 2 genes (shown are 17 most commonly occurring genes out of 153 Tier 2 cancer genes). (g) Spectrum of unique mutations (N=40) in most commonly mutated Tier 1 cancer genes (N=15). IPM, Institute for Precision Medicine.