Figure 2 | npj Genomic Medicine

Figure 2

From: Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care

Figure 2

EXaCT-1 sequencing quality metrics. The EXaCT-1 was validated using 57 archival samples with known mutations comprising a diverse representation of solid tumours and haematological cancers. Total reads, percentage of captured reads, average coverage and fraction of >10× covered bases by sample type (ad) and mutation-positive sample (eh) in FFPE (n=41) and fresh (n=16) tumour specimens. Additional QC metrics for all cases are available in Supplementary Tables 2 and 3. No statistically significant difference between FFPE and non-FFPE tissue and mutation-harbouring sample was observed in these analyses.

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