Table 2 Somatic mutations in known cancer genes

From: Somatic mutations in leukocytes infiltrating primary breast cancers

Sample Gene Mutation Frequency
1 EP300 p.G1777C 0.06
2 DNMT3A p.Y533C 0.185
3 EZH2 p.A483S 0.46
  TP53 p.M169I 0.029
4 BCOR p.P1156L 0.49
  EPHA7 p.G592S 0.14
  WT1 p.T278I 0.11
  TET2 p.Q1702* 0.06
  EGFR p.A871E 0.042
5 ALK p.R1209Q 0.21
  ETV6 p.P25S 0.038
6 NOTCH2 p.P1101T 0.18
  NF1 p.Q2434H 0.099
  SMARCA4 p.D694E 0.087
12 TET2 p.E1874K 0.17
  1. Mutations listed in this table were identified by targeted sequencing with an allele frequency of 10%. Mutations occurring at a lower frequency were included if previously reported in COSMIC.