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Biophysics

Cell commuters avoid delays

The rates of chemical reactions in a cell are limited by the time it takes the reactants to find each other through brownian motion. Thus diffusion determines the timescales of life — but can some reactions beat the diffusion limit?

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Figure 1: Transport network.

References

  1. Smoluchowski, M. V. Z. Phys. Chem. 92, 129–168 (1917).

    Google Scholar 

  2. Golding, I. & Cox, E. C. Phys. Rev. Lett. 96, 098102 (2006).

    Article  ADS  Google Scholar 

  3. Loverdo, C., Bénichou, O., Moreau, M. & Voituriez, R. Nature Phys. 4, 134–137 (2008).

    Article  ADS  Google Scholar 

  4. Adam, G. & Delbrück, M. in Structural Chemistry in Molecular Biology (eds Rich, A. & Davidson, N.) 198–215 (Freeman, San Francisco, 1968).

    Google Scholar 

  5. Richter, P. H. & Eigen, M. Biophys. Chem. 2, 255–263 (1974).

    Article  Google Scholar 

  6. Berg, O. G., Winter, R. B. & von Hippel, P. H. Biochemistry 20, 6929–6948 (1981).

    Article  Google Scholar 

  7. Coppey, M. et al. Biophys.J. 87, 1640–1649 (2004).

    Article  ADS  Google Scholar 

  8. Halford, S. E. & Marko, J. F. Nucleic Acids Res. 32, 3040–3052 (2004).

    Article  Google Scholar 

  9. Hu, T., Grosberg, A. Y. & Shklovskii, B. I. Biophys. J. 90, 2731–2744 (2006).

    Article  ADS  Google Scholar 

  10. Slutsky, M. & Mirny, L. A. Biophys. J. 87, 4021–4035 (2004).

    Article  ADS  Google Scholar 

  11. Wang, Y. M., Austin, R. H. & Cox, E. C. Phys. Rev. Lett. 97, 048302 (2006).

    Article  ADS  Google Scholar 

  12. Elf, J., Li, G. W. & Xie, X. S. Science 316, 1191–1194 (2007).

    Article  ADS  Google Scholar 

Download references

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Mirny, L. Cell commuters avoid delays. Nature Phys 4, 93–95 (2008). https://doi.org/10.1038/nphys848

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