Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Nanomedicine

An iron age for cancer therapy

Nature Nanotechnology volume 11, pages 921–922 (2016)Cite this article

Subjects

Two reports show FDA-approved nanoparticles can kill cancer cells through iron- and reactive oxygen species-dependent mechanisms, offering new strategies for cancer treatment.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Engineered nanoparticles kill cancer cells by manipulating iron levels and causing an accumulation of reactive oxygen species.

References

  1. Torti, S. V. & Torti, F. M. Nat. Rev. Cancer 13, 342–355 (2013).

    Article  CAS  Google Scholar 

  2. Trachootham, D., Alexandre, J. & Huang, P. Nat. Rev. Drug Discov. 8, 579–591 (2009).

    Article  CAS  Google Scholar 

  3. Kim, S. E. et al. Nat. Nanotech. 11, 977–985(2016).

    Article  CAS  Google Scholar 

  4. Zanganeh, S. et al. Nat. Nanotech. 11, 986–994 (2016).

    Article  CAS  Google Scholar 

  5. Dixon, S. J. et al. Cell 149, 1060–1072 (2012).

    Article  CAS  Google Scholar 

  6. Gao, M. et al. Mol. Cell 59, 298–308 (2015).

    Article  CAS  Google Scholar 

  7. Qian, B. Z. & Pollard, J. W. Cell 141, 39–51 (2010).

    Article  CAS  Google Scholar 

  8. Sarosiek, K. A. et al. Mol. Cell 51, 751–765 (2013).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Amy Tarangelo and Scott J. Dixon are in the Program in Cancer Biology and the Department of Biology, Stanford University, Room 104, 337 Campus Drive, Stanford, California 94305, USA,

    Amy Tarangelo & Scott J. Dixon

Authors
  1. Amy Tarangelo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Scott J. Dixon
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Scott J. Dixon.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tarangelo, A., Dixon, S. An iron age for cancer therapy. Nature Nanotech 11, 921–922 (2016). https://doi.org/10.1038/nnano.2016.199

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2016.199

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing