Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Nanobiotechnology

Net charge of trace proteins

Nature Nanotechnology volume 11, pages 739–740 (2016)Cite this article

Subjects

Isoelectric points of small samples of proteins can now be measured using atomic force microscopy and substrates with a known charge.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Measuring the isoelectric point of a protein by atomic force microscopy.

References

  1. Guo, S. et al. Nature Nanotech. 11, 817–823 (2016).

    Article  CAS  Google Scholar 

  2. Noy, A. Curr. Opin. Chem. Biol. 15, 710–718 (2011).

    Article  CAS  Google Scholar 

  3. Li, H. & Cao, Y. Acc. Chem. Res. 43, 1331–1341 (2010).

    Article  CAS  Google Scholar 

  4. Israelachvilli, J. Intermolecular and Surface Forces (Academic, 2011).

    Google Scholar 

  5. Sun, L. et al. Angew. Chem. Int. Ed. 52, 13661–13664 (2013).

    Article  CAS  Google Scholar 

  6. Shen, Y. & Smith, R. D. Electrophoresis 23, 3106–3124 (2002).

    Article  CAS  Google Scholar 

  7. Pihlasalo, S., Auranen, L., Hanninen, P. & Harma, H. Anal. Chem. 84, 8253–8258 (2012).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Gilbert C. Walker is in the Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada,

    Gilbert C. Walker

Authors
  1. Gilbert C. Walker
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gilbert C. Walker.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Walker, G. Net charge of trace proteins. Nature Nanotech 11, 739–740 (2016). https://doi.org/10.1038/nnano.2016.143

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2016.143

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing