Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Metabolic engineering

Enzyme control on a chip

Nature Nanotechnology volume 9, pages 571–572 (2014)Cite this article

Subjects

Electrical signals can be used to assemble and tune enzymes, resulting in controlled levels of optically, electrochemically and biologically active products.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Controlling enzymes with electrical signals.

References

  1. Hodgman, C. E. & Jewett, M. C. Metab. Eng. 14, 261–269 (2012).

    Article  CAS  Google Scholar 

  2. Jung, G. Y. & Stephanopoulos, G. Science 304, 428–431 (2004).

    Article  Google Scholar 

  3. Zawada, J. F. et al. Biotechnol. Bioeng. 108, 1570–1578 (2011).

    Article  CAS  Google Scholar 

  4. Zhang, Y. H. P., Evans, B. R., Mielenz, J. R., Hopkins, R. C. & Adams, M. W. W. PLoS ONE 2, e456 (2007).

    Article  Google Scholar 

  5. Mora-Pale, M., Sanchez-Rodriguez, S. P., Linhardt, R. J., Dordick, J. S. & Koffas, M. A. G. Plant Sci. 210, 10–24 (2013).

    Article  CAS  Google Scholar 

  6. Lewandowski, A. T. et al. Biotechnol. Prog. 24, 1042–1051 (2008).

    Article  CAS  Google Scholar 

  7. Gordonov, T. et al. Nature Nanotech. 9, 605–610 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Gretchen Mahler is in the Department of Bioengineering, Binghamton University, Binghamton, New York 13902, USA,

    Gretchen Mahler

Authors
  1. Gretchen Mahler
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gretchen Mahler.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mahler, G. Enzyme control on a chip. Nature Nanotech 9, 571–572 (2014). https://doi.org/10.1038/nnano.2014.160

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2014.160

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing