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Gene delivery

Cell-specific therapy on target


A polymer–lipid nanoparticle with a low molecular weight can preferentially deliver small interfering RNA to endothelial cells, offering an opportunity to treat many diseases.

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Figure 1: Small, multilamellar 7C1 nanoformulations selectively deliver siRNA to endothelial cells in vivo.


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Correspondence to Nigel A. J. McMillan.

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Clarke, D., McMillan, N. Cell-specific therapy on target. Nature Nanotech 9, 568–569 (2014).

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