Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Polymer nanoparticles

Weighing up gene delivery

Increasing the molecular weight of the core of a polymeric nanoparticle significantly improves its use in gene delivery.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: The selectivity of core/pegylated shell nanoparticles.

References

  1. McCormick, F. Nature Rev. Cancer 1, 130–141 (2001).

    CAS  Article  Google Scholar 

  2. Whitehead, K. A., Langer, R. & Anderson, D. G. Nature Rev. Drug Disc. 8, 129–138 (2009).

    CAS  Article  Google Scholar 

  3. De Smedt, S. C., Demeester, J. & Hennink, W. E. Pharm. Res. 17, 113–126 (2000).

    CAS  Article  Google Scholar 

  4. Chen, Y., Zhu, X., Zhang, X., Liu, B. & Huang, L. Mol. Therapy 18, 1650–1656 (2010).

    CAS  Article  Google Scholar 

  5. Yang, J. et al. Proc. Natl Acad. Sci. USA 110, 14717–14722 (2013).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jayanth Panyam.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kirtane, A., Panyam, J. Weighing up gene delivery. Nature Nanotech 8, 805–806 (2013). https://doi.org/10.1038/nnano.2013.234

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2013.234

This article is cited by

Search

Quick links

Find nanotechnology articles, nanomaterial data and patents all in one place. Visit Nano by Nature Research