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Molecular computing

In situ computation of cell identity

Cascade reactions can be used to carry out logic operations on the surface of cells and identify the presence of particular collections of cell surface markers.

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Figure 1: A three-input AND gate (A AND B AND C) using a programmed cascade of reactions on a cell surface.


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Correspondence to Peng Yin.

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Schaus, T., Yin, P. In situ computation of cell identity. Nature Nanotech 8, 546–548 (2013).

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