Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Atomic force microscopy

A tip for diagnosing cancer

Stiffness measurements of tumour biopsies and single cells show unique fingerprints that identify the different stages of cancer.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Prices vary by article type



Prices may be subject to local taxes which are calculated during checkout

Figure 1: Potential use of AFM in breast cancer diagnosis.


  1. Bushby, K. et al. Curr. Pediatrics 15, 292–300 (2005).

    Article  Google Scholar 

  2. Lekka, M. et al. Arch. Biochem. Biophys. 518, 151–156 (2012).

    Article  CAS  Google Scholar 

  3. Plodinec, M. et al. Nature Nanotech. 7, 757–765 (2012).

    Article  CAS  Google Scholar 

  4. Levental, K. R. et al. Cell 139, 891–906 (2009).

    Article  CAS  Google Scholar 

  5. Provenzano, P. et al. BMC Med. 6, 11 (2008).

    Article  Google Scholar 

  6. Prabhune, M. et al. Micron 43, 1267–1272 (2012).

    Article  Google Scholar 

  7. Moore, N. et al. Phys. Biol. 8, 010302 (2011).

    Article  CAS  Google Scholar 

  8. Kumar, S. & Weaver, V. M. Cancer Metast. Rev. 28, 113–127 (2009).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Małgorzata Lekka.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Lekka, M. A tip for diagnosing cancer. Nature Nanotech 7, 691–692 (2012).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Find nanotechnology articles, nanomaterial data and patents all in one place. Visit Nano by Nature Research