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In vitro studies

Ups and downs of cellular uptake

Nature Nanotechnology volume 6, pages 332–333 (2011)Cite this article

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Experiments on the uptake of gold nanoparticles by cells grown in different cell culture configurations suggest that the influence of sedimentation should be taken into account when performing in vitro studies.

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Figure 1: The variety of ways in which solid nanoparticles interact with cells (a) and behave in culture medium (b) make it difficult to define the relevant dose for nanotoxicology studies.

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Authors and Affiliations

  1. Dominique Lison and François Huaux are in the Louvain Centre for Toxicology and Applied Pharmacology, Avenue E. Mounier, 53.02, 1200 Brussels, Belgium.,

    Dominique Lison & François Huaux

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  1. Dominique Lison
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  2. François Huaux
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Correspondence to Dominique Lison or François Huaux.

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Lison, D., Huaux, F. Ups and downs of cellular uptake. Nature Nanotech 6, 332–333 (2011). https://doi.org/10.1038/nnano.2011.81

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