Neuroimaging studies of decision-making have generally related neural activity to objective measures (such as reward magnitude, probability or delay), despite choice preferences being subjective. However, economic theories posit that decision-makers behave as though different options have different subjective values. Here we use functional magnetic resonance imaging to show that neural activity in several brain regions—particularly the ventral striatum, medial prefrontal cortex and posterior cingulate cortex—tracks the revealed subjective value of delayed monetary rewards. This similarity provides unambiguous evidence that the subjective value of potential rewards is explicitly represented in the human brain.
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Weber, E.H. De Pulsu, Resorptione, Audita et Tactu. Annotationes Anatomicae et Physiologicae. (C.F. Koehler, Lipsiae, 1834).
Fechner, G.T. Elemente der Psychophysik (Breitkopf & Hartel, Leipzig, 1860).
Stevens, S. Neural events and the psychophysical law. Science 170, 1043–1050 (1970).
Bernoulli, D. The Works (Birkhauser, Boston, 1982).
Platt, M.L. & Glimcher, P.W. Neural correlates of decision variables in parietal cortex. Nature 400, 233–238 (1999).
Abler, B., Walter, H., Erk, S., Kammerer, H. & Spitzer, M. Prediction error as a linear function of reward probability is coded in human nucleus accumbens. Neuroimage 31, 790–795 (2006).
Cromwell, H.C. & Schultz, W. Effects of expectations for different reward magnitudes on neuronal activity in primate striatum. J. Neurophysiol. 89, 2823–2838 (2003).
Delgado, M.R., Nystrom, L.E., Fissell, C., Noll, D.C. & Fiez, J.A. Tracking the hemodynamic responses to reward and punishment in the striatum. J. Neurophysiol. 84, 3072–3077 (2000).
McCoy, A.N., Crowley, J.C., Haghighian, G., Dean, H.L. & Platt, M.L. Saccade reward signals in posterior cingulate cortex. Neuron 40, 1031–1040 (2003).
O'Doherty, J., Critchley, H., Deichmann, R. & Dolan, R.J. Dissociating valence of outcome from behavioral control in human orbital and ventral prefrontal cortices. J. Neurosci. 23, 7931–7939 (2003).
Breiter, H.C., Aharon, I., Kahneman, D., Dale, A. & Shizgal, P. Functional imaging of neural responses to expectancy and experience of monetary gains and losses. Neuron 30, 619–639 (2001).
Nieuwenhuis, S. et al. Activity in human reward-sensitive brain areas is strongly context dependent. Neuroimage 25, 1302–1309 (2005).
Rogers, R.D. et al. Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. Biol. Psychiatry 55, 594–602 (2004).
Kuhnen, C.M. & Knutson, B. The neural basis of financial risk taking. Neuron 47, 763–770 (2005).
Knutson, B., Taylor, J., Kaufman, M., Peterson, R. & Glover, G. Distributed neural representation of expected value. J. Neurosci. 25, 4806–4812 (2005).
Bowman, E.M., Aigner, T.G. & Richmond, B.J. Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards. J. Neurophysiol. 75, 1061–1073 (1996).
Cromwell, H.C., Hassani, O.K. & Schultz, W. Relative reward processing in primate striatum. Exp. Brain Res. 162, 520–525 (2005).
McCoy, A.N. & Platt, M.L. Risk-sensitive neurons in macaque posterior cingulate cortex. Nat. Neurosci. 8, 1220–1227 (2005).
Dorris, M.C. & Glimcher, P.W. Activity in posterior parietal cortex is correlated with the relative subjective desirability of action. Neuron 44, 365–378 (2004).
McClure, S.M. et al. Neural correlates of behavioral preference for culturally familiar drinks. Neuron 44, 379–387 (2004).
Gottfried, J.A., O'Doherty, J. & Dolan, R.J. Encoding predictive reward value in human amygdala and orbitofrontal cortex. Science 301, 1104–1107 (2003).
Tanaka, S.C. et al. Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops. Nat. Neurosci. 7, 887–893 (2004).
Padoa-Schioppa, C. & Assad, J.A. Neurons in the orbitofrontal cortex encode economic value. Nature 441, 223–226 (2006).
Daw, N.D., O'Doherty, J.P., Dayan, P., Seymour, B. & Dolan, R.J. Cortical substrates for exploratory decisions in humans. Nature 441, 876–879 (2006).
O'Doherty, J.P., Buchanan, T.W., Seymour, B. & Dolan, R.J. Predictive neural coding of reward preference involves dissociable responses in human ventral midbrain and ventral striatum. Neuron 49, 157–166 (2006).
Johnson, K.O., Hsiao, S.S. & Yoshioka, T. Neural coding and the basic law of psychophysics. Neuroscientist 8, 111–121 (2002).
Parker, A.J. & Newsome, W.T. Sense and the single neuron: probing the physiology of perception. Annu. Rev. Neurosci. 21, 227–277 (1998).
Werner, G. & Mountcastle, V.B. Quantitative relations between mechanical stimuli to the skin and neural responses evoked by them. in The Skin Senses (ed. Kenshalo, D.R.) 112–138 (Charles C Thomas Publisher, Springfield, Illinois, 1968).
Newsome, W.T., Britten, K.H. & Movshon, J.A. Neuronal correlates of a perceptual decision. Nature 341, 52–54 (1989).
Frederick, S., Loewenstein, G. & O'Donoghue, T. Time discounting and time preference: a critical review. J. Econ. Lit. 40, 351–401 (2002).
Mazur, J.E. An adjusting procedure for studying delayed reinforcement. in Quantitative Analysis of Behavior: The Effects of Delay and Intervening Events on Reinforcement Value (eds. Commons, M.L., Mazur, J.E., Nevin, J.A. & Rachlin, H.) 55–73 (Lawrence Erlbaum Associates, Publishers, Hillsdale, New Jersey, 1987).
Laibson, D. Golden eggs and hyperbolic discounting. Q. J. Econ. 12, 443–477 (1997).
Green, L. & Myerson, J. A discounting framework for choice with delayed and probabilistic rewards. Psychol. Bull. 130, 769–792 (2004).
Benhabib, J., Bisin, A. & Schotter, A. Present-bias, quasi-hyperbolic discounting and fixed costs. Working Paper (New York University Department of Economics, New York, 2006) <http://www.econ.nyu.edu/user/benhabib/pshype0106.pdf>.
McClure, S.M., Laibson, D.I., Loewenstein, G. & Cohen, J.D. Separate neural systems value immediate and delayed monetary rewards. Science 306, 503–507 (2004).
Teller, D.Y. & Pugh, E.N. Linking propositions in color vision. in Colour Vision: Physiology and Psychophysics (eds. Mollon, J.D. & Sharpe, L.T.) 577–589 (Academic Press, New York, 1983).
von Neumann, J. & Morgenstern, O. The Theory of Games and Economic Behavior (Princeton University Press, Princeton, New Jersey, 1944).
Samuelson, P.A. Foundations of Economic Analysis (Harvard University Press, Cambridge, Massachusetts, 1947).
Gul, F. & Pesendorfer, W. The case for mindless economics. Working Paper (Princeton University Department of Economics, Princeton, New Jersey, 2005) <http://www.princeton.edu/~pesendor/mindless.pdf>.
Gusnard, D.A. & Raichle, M.E. Searching for a baseline: functional imaging and the resting human brain. Nat. Rev. Neurosci. 2, 685–694 (2001).
Zysset, S., Huber, O., Ferstl, E. & von Cramon, D.Y. The anterior frontomedian cortex and evaluative judgment: an fMRI study. Neuroimage 15, 983–991 (2002).
Hsu, M., Bhatt, M., Adolphs, R., Tranel, D. & Camerer, C.F. Neural systems responding to degrees of uncertainty in human decision-making. Science 310, 1680–1683 (2005).
Paulus, M.P. & Frank, L.R. Anterior cingulate activity modulates nonlinear decision weight function of uncertain prospects. Neuroimage 30, 668–677 (2006).
Tom, S.M., Fox, C.R., Trepel, C. & Poldrack, R.A. The neural basis of loss aversion in decision-making under risk. Science 315, 515–518 (2007).
Sugrue, L.P., Corrado, G.S. & Newsome, W.T. Matching behavior and the representation of value in the parietal cortex. Science 304, 1782–1787 (2004).
Shadlen, M.N. & Newsome, W.T. Motion perception: seeing and deciding. Proc. Natl. Acad. Sci. USA 93, 628–633 (1996).
Collier, M. & Williams, M.B. Eliciting individual discount rates. Exp. Econ. 2, 107–127 (1999).
Camerer, C.F. & Hogarth, R.M. The effects of financial incentives in experiments: a review and capital-labor-production framework. J. Risk Uncertain. 19, 7–42 (1999).
Smith, V.L. & Walker, J.M. Monetary rewards and decision cost in experimental economics. Econ. Inq. 31, 245–261 (1993).
We thank A. Bisin, A. Caplin, M. Grantner, D. Heeger and I. Levy for their comments on earlier versions of this paper. This work was supported by grants from the National Institutes of Health (F32-MH75544 to J.W.K. and R01-NS054775 to P.W.G.), the McDonnell Foundation (to P.W.G.) and the Seaver Foundation.
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Kable, J., Glimcher, P. The neural correlates of subjective value during intertemporal choice. Nat Neurosci 10, 1625–1633 (2007). https://doi.org/10.1038/nn2007
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