Emotionally arousing events are recalled better than neutral events. This phenomenon, which helps us to remember important and potentially vital information, depends on the activation of noradrenergic transmission in the brain. Here we show that a deletion variant of ADRA2B, the gene encoding the α2b-adrenergic receptor, is related to enhanced emotional memory in healthy Swiss subjects and in survivors of the Rwandan civil war who experienced highly aversive emotional situations.
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This work was supported by grants from the Swiss National Science Foundation to D.J.-F.d.Q. (PP00B-106708) and A.P. (PP00B-68859), the Helmut-Horten Stiftung (A.P.), the Hermann-Klaus Stiftung (D.J.-F.d.Q.), the EMDO Stiftung (D.J.-F.d.Q.), the Olga Mayenfisch Stiftung (A.P., D.J.-F.d.Q.), the Novartis Foundation for Biomedical Research (A.P.), the German Research Foundation (751) and the vivo foundation (http://www.vivofoundation.net).
The authors declare no competing financial interests.
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de Quervain, DF., Kolassa, IT., Ertl, V. et al. A deletion variant of the α2b-adrenoceptor is related to emotional memory in Europeans and Africans. Nat Neurosci 10, 1137–1139 (2007). https://doi.org/10.1038/nn1945
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