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How can drug addiction help us understand obesity?

Nature Neuroscience volume 8, pages 555–560 (2005)Cite this article

To the degree that drugs and food activate common reward circuitry in the brain, drugs offer powerful tools for understanding the neural circuitry that mediates food-motivated habits and how this circuitry may be hijacked to cause appetitive behaviors to go awry.

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Figure 1: Dopaminergic pathways.
Figure 2
Figure 3: Role of dopamine D2 receptors in obesity.

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Acknowledgements

The authors thank C. Kassed for her assistance in preparing the manuscript.

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  1. National Institute on Drug Abuse, National Institutes of Health, Bethesda, 20892, Maryland, USA

    Nora D Volkow & Roy A Wise

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Volkow, N., Wise, R. How can drug addiction help us understand obesity?. Nat Neurosci 8, 555–560 (2005). https://doi.org/10.1038/nn1452

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