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Optic ataxia errors depend on remapped, not viewed, target location

Abstract

Optic ataxia is a disorder associated with posterior parietal lobe lesions, in which visually guided reaching errors typically occur for peripheral targets. It has been assumed that these errors are related to a faulty sensorimotor transformation of inputs from the 'ataxic visual field'. However, we show here that the errors observed in the contralesional field in optic ataxia depend on a dynamic gaze-centered internal representation of reach space.

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Figure 1: Fixation task and saccade–central viewing task.
Figure 2: Saccade–opposite field viewing task.

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Acknowledgements

We thank O.K. and C.F. for their participation and C. Urquizar, A. Blangero, M. Niemeier, J. Marotta and D. Pélisson for technical assistance and comments. This work was performed on the 'Mouvement et Handicap' platform (IFNL). This work was supported by Canadian Institutes of Health Research, Canada, and Institut National de la Santé et de la Recherche Médicale, Université Claude Bernard Lyon, and Programme Hospitalier de Recherche Clinique, France. J.D.C. is a Canada Research Chair.

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Correspondence to Y Rossetti.

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Khan, A., Pisella, L., Vighetto, A. et al. Optic ataxia errors depend on remapped, not viewed, target location. Nat Neurosci 8, 418–420 (2005). https://doi.org/10.1038/nn1425

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