Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Unraveling multisensory integration: patchy organization within human STS multisensory cortex


Although early sensory cortex is organized along dimensions encoded by receptor organs, little is known about the organization of higher areas in which different modalities are integrated. We investigated multisensory integration in human superior temporal sulcus using recent advances in parallel imaging to perform functional magnetic resonance imaging (fMRI) at very high resolution. These studies suggest a functional architecture in which information from different modalities is brought into close proximity via a patchy distribution of inputs, followed by integration in the intervening cortex.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Prices vary by article type



Prices may be subject to local taxes which are calculated during checkout

Figure 1: Patchy organization within the STS-MS.
Figure 2: Reliability of patchy organization within the STS-MS.


  1. Beauchamp, M.S., Lee, K.E., Argall, B.D. & Martin, A. Neuron 41, 809–823 (2004).

    Article  CAS  Google Scholar 

  2. Calvert, G.A. Cereb. Cortex 11, 1110–1123 (2001).

    Article  CAS  Google Scholar 

  3. Van Atteveldt, N., Formisano, E., Goebel, R. & Blomert, L. Neuron 43, 271–282 (2004).

    Article  CAS  Google Scholar 

  4. Wright, T.M., Pelphrey, K.A., Allison, T., McKeown, M.J. & McCarthy, G. Cereb. Cortex 13, 1034–1043 (2003).

    Article  Google Scholar 

  5. Hikosaka, K., Iwai, E., Saito, H. & Tanaka, K. J. Neurophysiol. 60, 1615–1637 (1988).

    Article  CAS  Google Scholar 

  6. Benevento, L.A., Fallon, J., Davis, B.J. & Rezak, M. Exp. Neurol. 57, 849–872 (1977).

    Article  CAS  Google Scholar 

  7. Seltzer, B. & Pandya, D.N. J. Comp. Neurol. 343, 445–463 (1994).

    Article  CAS  Google Scholar 

  8. Seltzer, B. et al. J. Comp. Neurol. 370, 173–190 (1996).

    Article  CAS  Google Scholar 

  9. Bodurka, J. et al. Magn. Reson. Med. 51, 165–171 (2004).

    Article  Google Scholar 

  10. De Zwart, J.A. et al. Magn. Reson. Med. 51, 22–26 (2004).

    Article  Google Scholar 

  11. Cheng, K., Waggoner, R.A. & Tanaka, K. Neuron 32, 359–374 (2001).

    Article  CAS  Google Scholar 

  12. Goodyear, B.G. & Menon, R.S. Hum. Brain Mapp. 14, 210–217 (2001).

    Article  CAS  Google Scholar 

  13. Beauchamp, M.S., Lee, K.E., Haxby, J.V. & Martin, A. Neuron 34, 149–159 (2002).

    Article  CAS  Google Scholar 

  14. Logothetis, N.K., Pauls, J., Augath, M., Trinath, T. & Oeltermann, A. Nature 412, 150–157 (2001).

    Article  CAS  Google Scholar 

  15. Wallace, M.T., Ramachandran, R. & Stein, B.E. Proc. Natl. Acad. Sci. USA 101, 2167–2172 (2004).

    Article  CAS  Google Scholar 

Download references


We thank C. Senior for providing the face stimuli and R.W. Cox and Z.S. Saad for their continued development of AFNI and SUMA.

Author information

Authors and Affiliations


Corresponding author

Correspondence to Michael S Beauchamp.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Video 1

Example of tool video used as visual stimulus (V) in main experiment. (MPG 330 kb)

Supplementary Video 2

Example of tool recording used as auditory stimulus (A) in main experiment. (MPG 216 kb)

Supplementary Video 3

Example of simultaneous video and recording used as auditory-visual stimulus (AV) in main experiment. (MPG 557 kb)

Supplementary Video 4

Example of face video used as visual stimulus (V) in control experiment. (MPG 1395 kb)

Supplementary Video 5

Example of voice recording used as auditory stimulus (A) in control experiment. (MPG 210 kb)

Supplementary Video 6

Example of simultaneous face video and voice recording used as auditory-visual stimulus (AV) in control experiment. (MPG 1395 kb)

Supplementary Discussion (PDF 29 kb)

Supplementary Methods (PDF 29 kb)

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Beauchamp, M., Argall, B., Bodurka, J. et al. Unraveling multisensory integration: patchy organization within human STS multisensory cortex. Nat Neurosci 7, 1190–1192 (2004).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing