Optogenetic stimulation of the locus coeruleus noradrenergic neurons can increase wakefulness, and high-frequency stimulation decreases noradrenaline levels and produces loss of muscle tone similar to that seen in cataplexy.
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McGregor, R., Siegel, J. Illuminating the locus coeruleus: control of posture and arousal. Nat Neurosci 13, 1448–1449 (2010). https://doi.org/10.1038/nn1210-1448
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DOI: https://doi.org/10.1038/nn1210-1448
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