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Hippocampal theta rhythms follow the beat of their own drum

The firing of most hippocampal neurons is modulated by the theta rhythm, but it's not clear how and where the rhythm is generated. A study now shows that the required machinery for theta generation lies in local circuits of the hippocampus.

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Figure 1: The upper trace shows theta recorded from the CA1 apical dendrites of a freely moving rat (L.L.C. and E.I.M., unpublished data), whereas the lower trace shows theta waves in the whole-hippocampus preparation of Goutagny et al.4 (their Fig. 1c).


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Correspondence to Edvard I Moser.

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Colgin, L., Moser, E. Hippocampal theta rhythms follow the beat of their own drum. Nat Neurosci 12, 1483–1484 (2009).

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