When the going gets tough, the cingulate gets going

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Despite extensive study, the exact role of human anterior cingulate cortex in forming behavioral strategies is still controversial. In this issue, Williams and colleagues describe a rare opportunity to test a hypothesis about the function of this brain area in humans, by not only recording from single neurons, but also monitoring behavior immediately after surgical ablation of the area.

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Figure 1: Experimental setup of Williams et al.

Ann Thompson

Figure 2: Example trial sequence.

Ann Thompson

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Gehring, W., Taylor, S. When the going gets tough, the cingulate gets going. Nat Neurosci 7, 1285–1287 (2004) doi:10.1038/nn1204-1285

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