The mature phenotype of CNS neurons is thought to be set at an early progenitor stage. A study now shows that expression of Fezf2 alone can turn striatal GABAergic precursors into glutamatergic corticofugal neurons.
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Götz, M. Making glutamatergic neurons from GABAergic progenitors. Nat Neurosci 13, 1308–1309 (2010). https://doi.org/10.1038/nn1110-1308
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DOI: https://doi.org/10.1038/nn1110-1308
