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Optimizing brain processing

Cholinergic neurons in the basal forebrain enable alert and attending brain states. A study now shows how basal forebrain activity increases coding abilities of cortical neurons and at what stages these changes occur.

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Figure 1: Mechanism by which decreased correlation and increased response reliability could be mediated by activation of the nucleus basalis.

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Correspondence to Alexander Thiele.

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Thiele, A. Optimizing brain processing. Nat Neurosci 12, 1359–1360 (2009). https://doi.org/10.1038/nn1109-1359

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