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Noisy neurons can certainly compute

How do neurons combine separate pieces of information that are only partially reliable? Surprisingly, their noise properties may simplify the underlying computations while allowing them to maintain optimal performance.

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Figure 1: Optimal pooling of unreliable signals is simplified by Poisson noise.


  1. Ma, W.J., Beck, J.M., Latham, P.E. & Pouget, A. Nat. Neurosci. 9, 1432–1438 (2006).

    Article  CAS  Google Scholar 

  2. Ernst, M.O. & Banks, M.S. Nature 415, 429–433 (2002).

    Article  CAS  Google Scholar 

  3. Kording, K.P. & Wolpert, D.M. Nature 427, 244–247 (2004).

    Article  Google Scholar 

  4. Miyazaki, M., Yamamoto, S., Uchida, S. & Kitazawa, S. Nat. Neurosci. 9, 875–877 (2006).

    Article  CAS  Google Scholar 

  5. Dean, A. Exp. Brain Res. 44, 437–440 (1981).

    Article  CAS  Google Scholar 

  6. Holt, G.R., Softky, W.R., Koch, C. & Douglas, R.J. J. Neurophysiol. 75, 1806–1814 (1996).

    Article  CAS  Google Scholar 

  7. Compte, A. et al. J. Neurophysiol. 90, 3441–3454 (2003).

    Article  Google Scholar 

  8. Van Vreeswijk, C. & Sompolinsky, H. Science 274, 1724–1726 (1996).

    Article  CAS  Google Scholar 

  9. Basalyga, G. & Salinas, E. Neural Comput. 18, 1349–1379 (2006).

    Article  Google Scholar 

  10. Softky, W.R. & Koch, C. J. Neurosci. 13, 334–350 (1993).

    Article  CAS  Google Scholar 

  11. Shadlen, M.N. & Newsome, W.T. Curr. Opin. Neurobiol. 4, 569–579 (1994).

    Article  CAS  Google Scholar 

  12. Stevens, C.F. & Zador, A.M. Nat Neurosci. 1, 210–217 (1998).

    Article  CAS  Google Scholar 

  13. Zemel, R.S., Dayan, P. & Pouget, A. Neural Comput. 10, 403–430 (1998).

    Article  CAS  Google Scholar 

  14. Jazayeri, M. & Movshon, J.A. Nat. Neurosci. 9, 690–696 (2006).

    Article  CAS  Google Scholar 

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Salinas, E. Noisy neurons can certainly compute. Nat Neurosci 9, 1349–1350 (2006).

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