Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Delivering the goods to synapses

Nature Neuroscience volume 3, pages 1064–1066 (2000)Cite this article

Zhu and colleagues show that delivery of AMPA receptors to synapses early in development is activity dependent and that it shares some, but not all, features with LTP.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Model suggested by Zhu et al.1

References

  1. Zhu, J. J., Esteban, J. A., Hayashi, Y. & Malinow, R. Nat. Neurosci. 3, 1098–1106 (2000).

    Article  CAS  Google Scholar 

  2. Malenka, R. C. & Nicoll, R. A. Science 285, 1870–1874 (1999).

    Article  CAS  Google Scholar 

  3. Malinow, R., Mainen, Z. F. & Hayashi, Y. Curr. Opin. Neurobiol. 10, 352–357 (2000).

    Article  CAS  Google Scholar 

  4. Feldman, D. E. & Knudsen, E. I. Neuron 20, 1067–1071 (1998).

    Article  CAS  Google Scholar 

  5. Hayashi, Y. et al. Science 287, 2262–2267 (2000).

    Article  CAS  Google Scholar 

  6. Dingledine, R., Borges, K., Bowie, D. & Traynelis, S. F. Pharmacol. Rev. 51, 7–61 (1999).

    CAS  Google Scholar 

  7. Frey, U. & Morris, R. G. Trends Neurosci. 21, 181–188 (1998).

    Article  CAS  Google Scholar 

  8. Rao, A. & Craig, A. M. Neuron 19, 801–812 (1997).

    Article  CAS  Google Scholar 

  9. O'Brien, R. J. et al. J. Neurosci. 17, 7339–7350 (1997).

    Article  CAS  Google Scholar 

  10. Gomperts, S. N., Carroll, R., Malenka, R. C. & Nicoll, R. A. J. Neurosci. 20, 2229–2237 (2000).

    Article  CAS  Google Scholar 

  11. Liao, D., Zhang, X., O'Brien, R., Ehlers, M. D. & Huganir, R. L. Nat. Neurosci. 2, 37–43 (1999).

    Article  CAS  Google Scholar 

  12. Friedman, H. V., Bresler, T., Garner, C. C. & Ziv, N. E. Neuron 27, 57–69 (2000).

    Article  CAS  Google Scholar 

  13. Turrigiano, G. G., Leslie, K. R., Desai, N. S., Rutherford, L. C. & Nelson, S. B. Nature 391, 892–896 (1998).

    Article  CAS  Google Scholar 

  14. O'Brien, R. J. et al. Neuron 21, 1067–1078 (1998).

    Article  CAS  Google Scholar 

  15. Carroll, R. C., Lissin, D. V., von Zastrow, M., Nicoll, R. A. & Malenka, R. C. Nat. Neurosci. 2, 454–460 (1999).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University School of Medicine, 1201 Welch Road, Rm. P105, Palo Alto, 94304, California, USA

    Reed C. Carroll & Robert C. Malenka

Authors
  1. Reed C. Carroll
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Robert C. Malenka
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Carroll, R., Malenka, R. Delivering the goods to synapses. Nat Neurosci 3, 1064–1066 (2000). https://doi.org/10.1038/80563

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/80563

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing