Orexin, drugs and motivated behaviors

  • A Corrigendum to this article was published on 01 December 2005

Orexins are known to regulate sleep and feeding, but a study in Nature now shows that they are also involved in drug-seeking behavior. This suggests a larger role for orexin-producing neurons as an interface between internal states and motivated behaviors.

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Figure 1: Pathways through which orexins may influence drug-seeking and other motivated behaviors.

Bob Crimi

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Scammell, T., Saper, C. Orexin, drugs and motivated behaviors. Nat Neurosci 8, 1286–1288 (2005). https://doi.org/10.1038/nn1005-1286

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