Wnts blow on NeuroD1 to promote adult neuron production and diversity

NeuroD1 is well known for its role in development. In this issue, two papers collectively show that the Wnt pathway directly activates the transcription factor NeuroD1 to regulate adult neurogenesis and, potentially, neuron diversity.

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Figure 1: Wnts control adult neurogenesis and LINE-1 recombination.

Katie Vicari

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Vanderhaeghen, P. Wnts blow on NeuroD1 to promote adult neuron production and diversity. Nat Neurosci 12, 1079–1081 (2009). https://doi.org/10.1038/nn0909-1079

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