How are objects represented in the brain during natural behavior? Visual object recognition in primates is thought to depend on the inferotemporal cortex (IT). In most neurophysiological studies of IT, monkeys hold their direction of gaze fixed while isolated visual stimuli are presented (controlled viewing). However, during natural behavior, primates visually explore cluttered environments by changing gaze direction several times each second (free viewing). We examined the effect of free viewing on IT neuronal responses in monkeys engaged in a form-recognition task. By making small, real-time stimulus adjustments, we produced nearly identically retinal stimulation during controlled and free viewing. Nearly 90% of neuronal responses were unaffected by free viewing, and average stimulus selectivity was unchanged. Thus, neuronal representations that likely underlie form recognition are virtually unaltered by free viewing.
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We thank C. Boudreau, E. Cook, G. Ghose, and T. Yang for discussions on design, analysis and presentation, and D. Murray for animal husbandry. We also thank K. Johnson and D. Sparks for comments on a previous version of this manuscript. This work was supported by NIH EY05911. J.H.R.M. is an Investigator with the Howard Hughes Medical Institute.
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DiCarlo, J., Maunsell, J. Form representation in monkey inferotemporal cortex is virtually unaltered by free viewing. Nat Neurosci 3, 814–821 (2000). https://doi.org/10.1038/77722
Shape-coding in IT cells generalizes over contrast and mirror reversal, but not figure-ground reversal
Nature Neuroscience (2001)
Nature Neuroscience (2000)