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The Na+ channel conundrum: axon structure versus function

Nature Neuroscience volume 13, pages 784785 (2010) | Download Citation

High Na+ channel density is thought to underlie the axon initial segment's (AIS's) low action potential initiation threshold, but a new study estimates functional Na+ channel density in the AIS is only threefold higher than in the soma.

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Author information

Affiliations

  1. The author is in the Center for Learning and Memory, University of Texas at Austin, Austin, Texas, USA.

    • Daniel Johnston

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Daniel Johnston.

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DOI

https://doi.org/10.1038/nn0710-784

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