Dendritic spines confine activity-dependent changes to the affected synapses. A paper in this issue reports that retarded diffusion in dendrites of aspiny interneurons may create dendritic biochemical compartments without spines.
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Ann Thomson
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Castillo, P., Khodakhah, K. Biochemical confinements without walls in aspiny neurons. Nat Neurosci 9, 719–720 (2006). https://doi.org/10.1038/nn0606-719
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DOI: https://doi.org/10.1038/nn0606-719
