Pyramidal neurons integrate synaptic inputs arriving on a structurally and functionally complex dendritic tree that has nonlinear responses. A study in this issue shows that nonlinear computation occurs in individual dendritic branches, and suggests a possible approach to building neural network models directly connected to the behavior of real neurons and synapses.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Proton Conducting Graphene Oxide/Chitosan Composite Electrolytes as Gate Dielectrics for New-Concept Devices
Scientific Reports Open Access 30 September 2016
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Polsky, A., Mel, B.W. & Schiller, J. Nat. Neurosci. 7, 621–627 (2004).
Dayan, P. & Abbott, L.F. Theoretical Neuroscience: Computational and Mathematical Modeling of Neural Systems (MIT Press, Cambridge, Massachusetts, USA, 2001).
Fausett, L.V. Fundamentals of Neural Networks (Prentice Hall, Upper Saddle River, New Jersey, USA, 1994).
Koch, C. & Segev, I. Nat. Neurosci. 3 (Suppl.), 1171–1177 (2000).
Williams, S.R. & Stuart, G.J. Trends Neurosci. 26, 147–154 (2003).
Hausser, M., Spruston, N. & Stuart, G.J. Science 290, 739–744 (2000).
Poirazi, P., Brannon, T. & Mel, B.W. Neuron 37, 977–987 (2003).
Schiller, J., Major, G., Koester, H.J. & Schiller, Y. Nature 404, 285–289 (2000).
Kampa, B.M., Clements, J., Jonas, P. & Stuart, G.J. J. Physiol. (Lond.) 556, 337–345 (2004).
Vargas-Caballero, M & Robinson, H.P. J. Neurophysiol. 89, 2778–2783 (2003).
Lester, R.A. & Jahr, C.E. J. Neurosci. 12, 635–643 (1992).
Larkum, M.E., Zhu, J.J. & Sakmann, B. J. Physiol. (Lond.) 533, 447–466 (2001).
Yuste, R., Gutnick, M.J., Saar, D., Delaney, K.R. & Tank, D.W. Neuron 13, 23–43 (1994).
Häusser, M. & Mel, B.W. Curr. Opin. Neurobiol. 13, 372–383 (2003).
Lorincz, A., Notomi, T., Tamas, G., Shigemoto, R. & Nusser, Z. Nat. Neurosci. 5, 1185–1193 (2002).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Spruston, N., Kath, W. Dendritic arithmetic. Nat Neurosci 7, 567–569 (2004). https://doi.org/10.1038/nn0604-567
Issue Date:
DOI: https://doi.org/10.1038/nn0604-567
This article is cited by
-
Proton Conducting Graphene Oxide/Chitosan Composite Electrolytes as Gate Dielectrics for New-Concept Devices
Scientific Reports (2016)
-
Pyramidal neurons: dendritic structure and synaptic integration
Nature Reviews Neuroscience (2008)
-
Recording, analysis, and function of dendritic voltage-gated channels
Pflügers Archiv - European Journal of Physiology (2006)