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Background K+ channels: an important target for volatile anesthetics?

Abstract

Some members of the 'two pore domain' K+ channel family are opened by volatile anesthetics. These channels may prove to be an important anesthetic target in mammals.

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Figure 1: Volatile general anesthetics activate background K+ channels.

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Franks, N., Lieb, W. Background K+ channels: an important target for volatile anesthetics?. Nat Neurosci 2, 395–396 (1999). https://doi.org/10.1038/8054

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